In acute myeloid leukemia (AML) quiescence and low oxidative state, linked to BCL2 mitochondrial regulation, endow leukemic stem cells (LSC) with treatment-resistance.LSC in CD34+ and more mature CD34- AML have heterogeneous immunophenotypes overlapping with normal stem/progenitor cells (copyright) but may be differentiated by functional markers.We
MODELS OF GOOD PRACTICE REGARDING SOCIAL SERVICES FOR THE ELDERLY IN ROMANIA - QUALITATIVE APPROACH
The elderly in Romania benefit from a set of social benefits and a wide range of social services depending on the needs identified by specialists.The main social services for seniors are residential centers, home care services and day centers.The aim of the paper is to present the models of good practice of social services for the Collections elder
Epigenetic Modifications in Stress Response Genes Associated With Childhood Trauma
Adverse childhood experiences (ACEs) may be referred to by other terms (e.g., early life adversity or stress and childhood trauma) and have a lifelong impact on mental and physical health.For example, childhood trauma has been associated with posttraumatic stress disorder (PTSD), anxiety, depression, bipolar disorder, diabetes, and cardiovascular d
Blending Control of Trolleybus Traction and Brake Drives to Enhance Braking Efficiency of Vehicle
The widespread use of green public transport is a priority strategy to reduce a congestion and pollution from road traffic in many cities.The trolleybus is a type of urban public electric transport, which is considered as a promising tool for increasing the efficiency of public transport and achieving the goals of sustainable development and qualit